Bromelain Drug Interactions

When taking certain medications with bromelain, it is possible for drug interactions to occur. Medicines that can negatively interact with bromelain include certain antibiotics and anticoagulant or antiplatelet medications. These interactions can alter the amount of medications in your blood, possibly increasing your risk of side effects. To avoid drug interactions, tell your healthcare provider about any other medicines, vitamins, or herbal supplements you are taking.

An Introduction to Bromelain Interactions

Even though it is a "natural" product, bromelain can potentially interact with certain medications. In particular, it is thought that bromelain could theoretically interact with the following medicines:
 
  • Certain antibiotics, such as:

 

 

  • Anticoagulant or antiplatelet medications ("blood thinners"), such as:

 

    • Aspirin (Bayer® and others)
    • Cilostazol (Pletal®)
    • Clopidogrel (Plavix®)
    • Dipyridamole (Persantine®)
    • Eptifibatide (Integrilin®)
    • Heparin or heparin-like products, including dalteparin (Fragmin®), enoxaparin (Lovenox®), or tinzaparin (Innohep®)
    • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

 

 

 


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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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