Bromelain

As a type of enzyme found in pineapple, bromelain may have several medicinal properties. For instance, it may aid in digestion, reduce inflammation, and help to break down blood clots. Although there is little scientific evidence to support the effectiveness of this product for most uses, preliminary research suggests promise for a few uses. Possible side effects of the supplement may include stomach upset and allergic reactions.

What Is Bromelain?

Bromelain is a name for enzymes found in pineapple. These enzymes can dissolve protein and are used to tenderize meat and as nutritional supplements. Bromelain is thought to aid in digestion and reduce inflammation. It may also have activity against cancer and blood clots.
 
(Click Benefits of Bromelain for more information on what the supplement is used for.)
 

How Does It Work?

Bromelain is a mixture of proteolytic (protein-dissolving) enzymes. It contains substances that may slow down the growth of cancerous cells, decrease the "stickiness" of blood platelets, help to break down blood clots, and help to break down and remove dead, damaged, or infected tissue (such as in burn wounds). It may also affect the way white blood cells function, which may produce anti-inflammatory properties.
 

Is Bromelain Effective?

In general, there is little scientific evidence to suggest conclusively that the supplement really is effective for most uses. However, early research shows promise for a few different uses (see Does Bromelain Work? for more information).
 

Dosing Information

As with most dietary supplements, there is no well-established standard dosage for this product, although general guidelines may be obtained from a few clinical trials of bromelain products or from information on use in other countries.
 
(Click Bromelain Dosage for more information.)
 

Side Effects of Bromelain

Even though it is a "natural" product, bromelain can cause side effects. Some of the reported side effects include:
 
  • Stomach upset
  • Diarrhea
  • Allergic reactions.
     
(Click Bromelain Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 

Drug Interactions

Theoretically, the supplement may interact with a few medications (see Bromelain Drug Interactions).
 

Safety of Bromelain

Bromelain seems to be relatively safe for many people, especially when used in moderation. Some people may be more likely to experience problems due to this substance. Therefore, you should talk with your healthcare provider prior to taking it medicinally if you:
 
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Is Bromelain Safe? for more information, including any available warnings and precautions.)
 

What If I Take an Overdose?

It is not known what exactly to expect from an overdose of this supplement. If you think you or someone else may have taken too much, it is important to seek immediate medical attention.
 
(Click Bromelain Overdose for more information.)
 

Storage Methods for Bromelain

Refer to the label of your individual product for information on how best to store bromelain. Keep all medications and supplements out of the reach of children.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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