Drugs That Can Interfere With DuoNeb

DuoNeb Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when DuoNeb is combined with any of the drugs listed above.
Acetylcholinesterase Inhibitors
Taking DuoNeb with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring.
Anticholinergic Medications
Combining an anticholinergic medication with DuoNeb (which also contains an anticholinergic medication) can increase your risk of DuoNeb side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine.
Beta Blockers
Taking DuoNeb and a beta blocker together can decrease the effectiveness of both medications. In addition, sometimes beta blockers can have a negative effect on chronic obstructive pulmonary disease (COPD). While some beta blockers are less likely than others to interact with DuoNeb, all beta blockers can potentially cause problems.
Certain Diuretics
Combining DuoNeb and certain diuretics can increase your risk of low potassium levels (hypokalemia), especially if you use DuoNeb more frequently than recommended. Talk to your healthcare provider before using these medications together.
DuoNeb may decrease the level of digoxin in your blood, perhaps making it less effective. Your healthcare provider may need to monitor the level of digoxin in your blood and adjust your digoxin dosage as necessary, especially when you are starting or stopping DuoNeb.
Monoamine Oxidase Inhibitors
DuoNeb should be used with extreme caution in combination with MAOIs, as it may result in dangerously low blood pressure (hypotension). Talk to your healthcare provider before combining these medications.

DuoNeb Inhalation Solution

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