Drug Interactions With Levalbuterol (Cont.)

Levalbuterol Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when levalbuterol is combined with any of the drugs listed above.
 
Beta Blockers
Taking levalbuterol and a beta blocker together can decrease the effectiveness of both medications. People with asthma should generally avoid beta blockers, as they may worsen their condition. While some beta blockers are less likely than others to interact with levalbuterol, all beta blockers can potentially cause problems.
 
Certain Diuretics
Taking levalbuterol and certain diuretics together can increase your risk of low potassium levels (hypokalemia), especially when you use levalbuterol more frequently than recommended. Talk to your healthcare provider before using these medications together.
 
Digoxin
Levalbuterol may decrease the level of digoxin in your blood, perhaps making it less effective. Your healthcare provider may need to monitor the level of digoxin in your blood and adjust your digoxin dosage as necessary, especially when you are starting or stopping levalbuterol.
 
Monoamine Oxidase Inhibitors
Levalbuterol should be used with extreme caution in combination with MAOIs because it may result in dangerously low blood pressure (hypotension). Talk to your healthcare provider before combining levalbuterol with an MAOI.
 
Tricyclic Antidepressants
Levalbuterol should be used with extreme caution in combination with tricyclic antidepressants because it may result in dangerously low blood pressure (hypotension) or an irregular heart rhythm (arrhythmia). Talk to your healthcare provider before combining these two medications.
 
(Drug Interactions With Levalbuterol Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;