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Drug Interactions With Levalbuterol
Drug interactions with levalbuterol may occur with a variety of medications, such as beta blockers, certain diuretics, MAOIs, or tricyclic antidepressants. Some of these interactions can decrease the effectiveness of the medications and may lead to low potassium levels, dangerously low blood pressure, or an irregular heart rhythm. If drug interactions with levalbuterol are a concern, your healthcare provider may adjust your dosages.
Levalbuterol hydrochloride (Xopenex®) can potentially interact with a few other medicines. Some of these medicines that may lead to drug interactions with levalbuterol include:
- Beta blockers, such as:
- Atenolol (Tenormin®)
- Bisoprolol (Zebeta®)
- Metoprolol (Lopressor®, Toprol XL®)
- Nadolol (Corgard®)
- Propranolol (Inderal®)
- Sotalol (Betapace®)
- Timolol (Blocadren®)
- Carvedilol (Coreg®)
- Labetalol (Trandate®)
- Certain diuretics, such as:
- Bumetanide (Bumex®)
- Chlorothiazide (Diuril®)
- Chlorthalidone (Thalitone®)
- Ethacrynic acid (Edecrin®)
- Furosemide (Lasix®)
- Hydrochlorothiazide (Esidrix®, HydroDIURIL®, Microzide®, Oretic®)
- Metolazone (Zaroxolyn®)
- Torsemide (Demadex®)
- Isocarboxazid (Marplan®)
- Phenelzine (Nardil®)
- Rasagiline (Azilect®)
- Selegiline (Eldepryl®, Emsam®, Zelapar®)
- Tranylcypromine (Parnate®)
- Tricyclic antidepressants, including:
- Amoxapine (Asendin®)
- Clomipramine (Anafranil®)
- Desipramine (Norpramin®)
- Doxepin (Sinequan®, Silenor®)
- Imipramine (Tofranil®, Tofranil PM®)
- Maprotiline (Ludiomil®)
- Nortriptyline (Pamelor®)
- Protriptyline (Vivactil®)
- Trimipramine (Surmontil®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD