COPD Home > Daliresp and Weight Loss
Some people may experience weight loss as a side effect of Daliresp (roflumilast). This medicine has several side effects that can contribute to weight loss, including nausea, diarrhea, and a loss of appetite. Although weight loss can be a good thing for some people, it can be a problem for others. If weight loss becomes a problem during treatment, let your healthcare provider know.
An Overview of Daliresp and Weight LossDaliresp™ (roflumilast) is a prescription medication used to treat chronic obstructive pulmonary disease (COPD). Weight loss is one of the potentially serious side effects of Daliresp.
How Common Is Weight Loss With Daliresp?In a yearlong clinical study, up to 20 percent of people taking Daliresp experienced moderate weight loss (defined as 5 to 10 percent of body weight), compared to about 7 percent of people taking a placebo (a "sugar pill" that does not contain any active ingredients). Additionally, up to 7 percent of people taking Daliresp experienced severe weight loss (defined as more than 10 percent of body weight), compared to 2 percent of people taking the placebo.
Daliresp often causes a loss of appetite, nausea, and diarrhea, which may contribute to weight loss.
Although weight loss can be a desirable side effect for some people, too much weight loss can be a problem, especially in frail, elderly people. If you take Daliresp, you should be weighed regularly to make sure you are not losing too much weight.