DuoNeb is commonly prescribed to treat symptoms of chronic obstructive pulmonary disease. This prescription medication comes in liquid form and is inhaled using a nebulizer. It consists of two medications (albuterol and ipratropium), and works by binding to specific receptors in the airways, relaxing the muscles around them and allowing more air to get into and through the lungs. Possible side effects include sore throat, chest pain, and diarrhea.
DuoNeb is approved for treating COPD in people who need more than one medication to prevent airway spasms. The medication is inhaled using a nebulizer -- a device that changes liquid medications into fine droplets that are inhaled into the lungs.
The ipratropium component of DuoNeb belongs to a group of medications known as anticholinergics or antimuscarinics. By binding to specific receptors in the airway, called muscarinic receptors, ipratropium helps to relax the smooth muscle of the airway and allow more air into and out of the lungs.
The other component, albuterol, belongs to a class of drugs called beta-adrenergic receptor agonists, or beta agonists for short. Beta agonists stimulate beta receptors in the body, including those on the muscles around airways. This stimulation causes the muscles to relax, which opens up the airways and allows more air to get into and through the lungs.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed September 7, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins;2005.
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