Perforomist is used to treat the symptoms of chronic obstructive pulmonary disease (COPD). It works by relaxing the muscles around the airways to allow more air into and through the lungs. The medication comes in the form of a liquid and is inhaled into the lungs using a nebulizer. Potential side effects include diarrhea, nausea, and a dry mouth.
Normally, air moves easily into and out of the lungs through a network of airways. However, certain lung diseases (such as asthma or COPD) cause the muscles around these airways to tighten. This narrows the airways and makes it harder to breathe. This is called bronchospasm.
Perforomist is part of a class of drugs called beta-adrenergic receptor agonists, or beta agonists for short. Beta agonists stimulate beta receptors in the body, including those on the muscles around the airways. This stimulation causes the muscles to relax, which opens up the airways and allows more air to get into and through the lungs. Perforomist also has some effects on decreasing the activity of mast cells in the lungs, which play an important role in inflammation and allergic reactions.
Beta agonists are usually divided into two categories, short-acting and long-acting beta agonists. Perforomist is a long-acting beta agonist.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed December 3, 2007.
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