Terbutaline and Preterm Labor (Cont.)

Terbutaline and Preterm Labor Risks

Terbutaline has been given a pregnancy Category B rating, which means that it is probably safe for use during pregnancy (see Terbutaline and Pregnancy). However, the manufacturer of terbutaline specifically warns that it should not be used for preterm labor. This warning is not supported by scientific evidence and was most likely included for legal reasons. However, using terbutaline is not without risks. The following side effects may occur in the mother:
 
  • Irregular heart rhythms (arrhythmias)
  • Pulmonary edema (fluid in the lungs)
  • Decreased blood flow to the heart
  • Low blood pressure (hypotension)
  • A rapid heart rate (tachycardia).
     
Among the side effects that may occur in the infant are:
 
  • A rapid heart rate (tachycardia)
  • High insulin levels
  • High blood sugar (hyperglycemia)
  • Decreased blood flow to the heart
  • Other heart problems.
     

Final Thoughts on Terbutaline and Preterm Labor

Despite warnings from the manufacturer, terbutaline is generally considered a good treatment for delaying preterm labor. It can provide enough time to ensure that the premature infant's lungs develop properly. However, it is not without risk, and is not approved for this use. Be sure to talk with your healthcare provider about terbutaline and preterm labor for your particular situation. Together you can weigh the potential risks and benefits.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;